منابع مشابه
Congenital hypoplastic anemia inhibition of erythropoiesis by sera from patients with congenital hypoplastic anemia.
An in vitro marrow culture assay designed to measure erythropoietic capability was used to ascertain the presence of an inhibitor in the sera of patients with congenital hypoplastic anemia (CHA). Marrow cells from nine anemic CHA patients responded to the stimulatory effect of exogenous erythropoietin (EPO) by an increase in heme synthesis in the presence of normal serum. The effect on heme syn...
متن کاملLymphocyte dysfunction in congenital hypoplastic anemia.
Congenital hypoplastic anemia (Diamond-Blackfan syndrome) is thought to involve the erythropoietic cell line alone. In this study, the evaluation of lymphocyte function in five patients with this syndrome revealed a number of abnormalities. Peripheral blood T lymphocyte percentages as assessed by monoclonal antibodies were decreased in three patients. T-helper/T-suppressor cell (OKT4:OKT8) rati...
متن کاملAnæmia in Practice: Pernicious Anæmia
Thirteen years ago, Drs. G. R. Minot and W. P. Murphy published a paper in the Journal of the American Medical Association describing the effect of liver diet in pernicious anaemia. This was a clinical study, but the results were striking enough to attract a considerable amount of attention, not only of clinicians but of laboratory workers as well. The immediate direct result was a revolutionar...
متن کاملCongenital (erythroid) hypoplastic anaemia: modified expression in males.
Intractable anaemia beginning soon after birth or in the first few months of life, and due to a hypoplastic state of the bone-marrow, is rare. As case reports have accumulated, it has become clear that this rather broad description includes a variety of syndromes. One of these, first described briefly by Josephs (1938) and Diamond and Blackfan (1938), has come to be recognized as a clearlydefin...
متن کاملCongenital hypoplastic thrombocytopenia with skeletal deformaties in siblings.
By SIDNEY SHAw AND R. A. M. OLIVER H AUSERTM described a case of primary congenital aphasia of megakaryocytes with other congenital deformities. Several other instances of a similar condition associated with absent radii have recently been reviewed by Emery, Gordon, Rendle-Short, Varadi and Warrack.1 Gross, Groh and Weippl7 have described four cases of congenital hypoplastic thrombocytopenia wi...
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ژورنال
عنوان ژورنال: Proceedings of the Royal Society of Medicine
سال: 1966
ISSN: 0035-9157
DOI: 10.1177/003591576605900606